ea0031s12.4 | Thymic function and autoimmune endocrine disease | SFEBES2013
Sansom David
The T cell immune system exists in a state of balance, poised to react to invading pathogens but at the same time constantly being restrained from attacking our own tissues. Several strategies are employed in order to minimise our own self-reactivity. First amongst these processes is the deletion of T cells in the thymus, however this process is incomplete and self-reactive T cells still populate our immune systems. A second layer of control is exerted by regulatory T cells (T...